Biotech & Health

A road map for climate investors

Comment

Forest in the shape of arrow sign on a yellow background.
Image Credits: Andriy Onufriyenko (opens in a new window) / Getty Images

Arvind Gupta

Contributor

Arvind Gupta co-leads Mayfield’s engineering biology practice and is founder and venture adviser at IndieBio. He is the co-author of “Decoding the World,” published by Hachette.

Climate in the last decade has been unprecedented in many ways, none of them good.

Wildfires in California have consumed entire towns; thousands of miles away, New Yorkers inhale the ashes. Across Europe and Japan, flash floods wreak widespread devastation. We all see the videos on YouTube and CNN. And we shrug.

The recently released 6th Intergovernmental Panel on Climate Change report concluded that human-created climate change is taking place faster than we thought, calling it a “code-red alert.” At just 2 degrees warmer than today, one estimate predicts more than 300,000,000 climate-related deaths globally by 2100. And that’s the optimistic estimate. Global warming is overwhelming and feels impossible to fix. What the hell can we do?

Like many of you, I am an optimist. Humanity has come to the limits of nature many times in the past and has overcome them with technology. We have always adapted ourselves to our environment; changing our technology and behavior due to environmental change is part of our history.

Regulation will help incentivize corporations to clean up, but only technology can solve the intractable problem of sustainably giving us what we desire. Thoughtless consumption brought us climate change, but it is also true that mindful consumption can get us out of it.

How do we use capitalism to eliminate greenhouse gas emissions worldwide? Follow the carbon. That leads us to the three main bottlenecks on the road to net-zero carbon emissions.

What follows is necessarily a high-level overview of huge and complex industries. I’ve purposely left out granular details so we could address the overarching issues.

Electrification: 36 gigatons CO2 emitted

TAM: $7 trillion

Global carbon usage is highest in energy production as we burn coal, oil and natural gas to power our cars, cities and industry (yes, coal is still mined and burned in 2021). That’s a whopping 36 gigatons of CO2 emissions per year. Why do we still burn coal? It’s cheap, on-demand, universal, portable, an order of magnitude more efficient than lithium-ion batteries and much safer.

But it needs to be eliminated, very soon.

The IPCC report found that 89% of global CO2 emissions come from fossil fuels. Further, it tells us we must cut these emissions in half over the next decade or risk a 1.5-degree Celsius increase in average global temperatures.

Currently, wind and solar cannot produce electricity 100% of the time; generated energy must be stored rather than just dumped if unused, as it is done today. There are many ways of producing clean energy today, including nuclear, tidal, hydroelectric, geothermal and other means. Fusion is advancing every year.

We will need more than double today’s clean energy output to service growing demand. But until we can store this energy and use it in cars, boats, airplanes and more, clean energy production will not eliminate the need for oil and coal. Energy storage is the main bottleneck for a global electric economy. We need bigger, safer and cleaner batteries that can be used everywhere from the grid to our cars to our homes and keep the lights on when we need them most.

You and I won’t be buying these batteries, but they will power everything we do buy. From cars to the cargo ships that deliver them to the airplanes that carry us, they will all eventually be electric. Boeing just ordered 100 electric planes from Heart Aerospace, in which it also invested. The world’s first electric cargo ship, the Yara Birkeland, built by Marin Teknikk, is scheduled to have its maiden voyage soon.

There are no fewer than a dozen electric aircraft companies and six dozen electric vehicle companies. But the bottleneck for these efforts to scale and replace all fossil fuel planes, ships and cars with equivalent performance is a humble battery capable of delivering sustained, high power output over a long period of time. Without that fundamental advancement, these companies will stay in the conceptual stage for a long time.

Unfortunately, lithium-based battery technology still only has one-tenth the maximum energy density of gasoline (which is around 50 megajoules per kilogram). It isn’t enough. The closest we can get with lithium-ion technology is the lithium-air battery, which has a theoretical energy density of 40 megajoules per kilogram, but new electrolytes need to be invented for it to work. Like Chuck Yeager breaking the sound barrier to usher in the supersonic era, we need to break through this density barrier to power our green future.

Recent studies have demonstrated that melanin, our skin pigment, has also shown promise as a potent cathode that can make rechargeable sodium batteries a possibility. This would enable large-scale “salt” batteries that can be used to create a safe and clean grid storage solution. Researchers have also used viruses to create nanolayers of different elements to make higher-performance cathodes. Other lines of research have shown that batteries driven by enzymatic catalysts can potentially use sugar water to slowly charge your car or house with bio-electricity. None of the solutions above are within a decade to market; all are in the research stage.

The winners of the electrification wars will aggregate these technologies across industries and provide consumers with a seamless, wonderful experience. From fast wireless charging of electronics and vehicles to self-adapting national electrical grids, an electrified world will be quieter, efficient and clean. I am excited about the prospect of living in a fully electric world.

Rematerialization: 10.2 gigatons emitted

TAM: $12 trillion

Every object in the room you’re sitting in was made unsustainably and reeks of carbon emissions. The cement floor, sofa, dining table, desk, refrigerator, sink, chairs, even the walls contribute to climate change. Consumers have no choice; they can’t buy green, and we need to change this.

Durable goods and our built environment alone account for more than 10.2 gigatons of CO2 emissions yearly, or nearly one-third of total emissions. The heights of dirty industry need to be toppled and rebuilt from scratch with a new goal in mind: Sustainable production for hundreds of years to come.

Cement

Global cement production emits nearly 2.5 gigatons of carbon dioxide per year. There are dozens of green cement companies now trying various approaches to eliminating CO2 emissions from cement and concrete. At IndieBio, I invested in Carbix, a company that takes CO2 emissions and uses them to make olivine cement. They have made a few bricks and are years from the market.

The main barrier for most green cement formulators is proving equivalent structural performance. Getting to scale is expensive. However, a few companies promising greener concrete are coming to market in the next few years.

Steel

Making steel and aluminum is energy-intensive. In fact, aluminum is referred to by many commodity traders as “energy in solid form.” Powering our foundries with clean energy and reducing their carbon usage will help eliminate 8% of emissions.

Wood

Trees are our biggest carbon sinks. They suck in CO2 from the air and exhale the oxygen we breathe. So why do we still cut them down?

Hopefully, soon we won’t have to. Companies are using flax and other natural fibers to create bio-composites that are stiffer than steel and lighter than wood, or developing sustainable bamboo for exterior building panels. Others are experimenting with mushroom mycelium to grow entire buildings.

Leather and fabrics

Cows contribute 7.1 gigatons of CO2 per year to global warming, a full 14.5% of the total. We don’t just eat them, we use their skin a lot. Leather is everywhere, from shoes and couches to purses and clothing. We need to replace this material if we are to eliminate cows from our supply chain.

Fortunately, a dozen companies are making headway into eliminating plastic and leather from fashion. All are finding tremendous traction with consumer companies looking to provide their consumers with vegan and sustainable products.

Fabrics like polyester are made of petrochemicals. Fermentation technologies excel at making oils from sugar water by using algae or yeast as a factory. Fermentation is scalable and exists today, while a newer technology called cell-free synthesis is being applied to these same problems. We can expect new green fabrics in the next five years.

Industrial chemicals

Break down oil and you get a list of unpronounceable names that make much of our world. These chemicals are used in engines, antifreeze, cosmetics and even foods. To eliminate any need for oil, these products must be replaced through fermentation, which converts sugar into chemicals.

The sugar can come from corn or even waste CO2 in chimneys. Cells don’t have to be alive either, as cell-free synthesis allows the enzymes themselves to do the work. A huge number of companies have been started to remake all these chemicals through varieties of fermentation and synthesis.

Rematerializing our planet with sustainable, carbon-neutral sources can remove up to 10 gigatons of emissions from our economy. Our houses and everything inside them will eventually become carbon-neutral through rematerialization. I am excited about breaking this bottleneck to progress because it naturally leads to better products for everyone.

Food: 3.6 gigatons C02 emitted

TAM: $10 trillion

The first slide of a presentation I gave to explain the new food revolution depicted cavemen with spears being mauled by a giant prehistoric bear. The point? Protein is important enough to die for. As we transitioned from hunting to farming, our society reorganized around cities and the division of labor.

Civilization was born alongside the sheep and cow, but 10,000 years later, the sheep, cow and pig are killing us. They emit 10% of global greenhouse gases, and global demand for meat is skyrocketing. Over the past six years at IndieBio, I’ve invested in Clara Foods, Geltor, Memphis Meats (now Upside Foods), NotCo and many others to reinvent agriculture through fermentation, plant-based formulations and cell-based culture.

These startups reinvented familiar foods like burgers, mayonnaise, popcorn shrimp, egg whites, poke bowls, sausages and chicken wings. As affluent societies began eating more processed foods, foods became products: Cows became burgers, pigs became bacon and chickens are now nuggets. A legion of food-as-product companies have followed in their footsteps and there are entire conferences dedicated to them. “Food is hot” is an understatement in Silicon Valley.

Having been a part of the food revolution from its earliest days, I am struck by the magnitude of these revolutions once they really get going. I am also wary of revolutions that stall. Cell-based foods should be on the market next year and consumers will get to decide for themselves if the revolution is for them. So the final shape and form of the world once the revolutions roll through society and become the new normal is not easy to predict.

I am a fan of history, so I look into the past to see where we are going next. My mother’s recipe for curry chicken is a good place to start. It calls for chicken thighs with the bone in, chopped. If I want to make a low-carbon, animal-free version of that recipe, I’d have to use something other than chicken, but what? Just’s cell-based chicken nuggets? No, breaded chicken nuggets won’t work, nor would soy alternatives. Beyond Curry? My mom wouldn’t approve.

Biofarming real food

For agriculture to be reinvented for everyone, not just the 1%, we must make food. Real, natural food. Steaks, chicken breasts and thighs, bone-in meats and spare ribs. Not a processed version of these products, but ingredients to make whole-food dishes.

Food 3.0 is biofarming. Biofarming will have to solve for taste and wholesome nutrition. Delicious foods with no processing other than mom’s recipe. Regenerative agriculture will enable carbon-neutral vegetables and plants if we can help farmers get their yields high enough to turn a profit while a field is fallow for a season. Numerous technologies are helping to achieve this.

We aren’t F’d yet

Bloomberg recently reported that there have been over 5 million deaths a year globally from climate change-related events from 2009 to 2019. That’s one in 10 deaths on the planet. Since we do not track this statistic (we track heat stroke, drowning, landslide, suicide and the things that directly kill us), nor other effects like people not having children and extreme anxiety, it is impossible to know the true magnitude of misery climate change will bring. How far will we let this go before we all act? How many more will have to die?

The new normal doesn’t need to be this way. Scientists can choose to apply their work to solve the paradox of carbon and production. Investors can choose to put money into companies rebuilding our world to be gentle and green. And entrepreneurs can choose to build companies that reshape our carbon economy for the greatest opportunity in history. The above road map represents the ability to erase nearly all carbon emissions by humanity.

We are far from doomed. Together, we will all build and we will all fight for our future.

More TechCrunch

On Friday, Pal Kovacs was listening to the long-awaited new album from rock and metal giants Bring Me The Horizon when he noticed a strange sound at the end of…

Rock band’s hidden hacking-themed website gets hacked

Jan Leike, a leading AI researcher who earlier this month resigned from OpenAI before publicly criticizing the company’s approach to AI safety, has joined OpenAI rival Anthropic to lead a…

Anthropic hires former OpenAI safety lead to head up new team

Welcome to TechCrunch Fintech! This week, we’re looking at the long-term implications of Synapse’s bankruptcy on the fintech sector, Majority’s impressive ARR milestone, and more!  To get a roundup of…

The demise of BaaS fintech Synapse could derail the funding prospects for other startups in the space

YouTube’s free Playables don’t directly challenge the app store model or break Apple’s rules. However, they do compete with the App Store’s free games.

YouTube’s free games catalog ‘Playables’ rolls out to all users

Featured Article

A comprehensive list of 2024 tech layoffs

The tech layoff wave is still going strong in 2024. Following significant workforce reductions in 2022 and 2023, this year has already seen 60,000 job cuts across 254 companies, according to independent layoffs tracker Layoffs.fyi. Companies like Tesla, Amazon, Google, TikTok, Snap and Microsoft have conducted sizable layoffs in the first months of 2024. Smaller-sized…

3 hours ago
A comprehensive list of 2024 tech layoffs

OpenAI has formed a new committee to oversee “critical” safety and security decisions related to the company’s projects and operations. But, in a move that’s sure to raise the ire…

OpenAI’s new safety committee is made up of all insiders

Time is running out for tech enthusiasts and entrepreneurs to secure their early-bird tickets for TechCrunch Disrupt 2024! With only four days left until the May 31 deadline, now is…

Early bird gets the savings — 4 days left for Disrupt sale

AI may not be up to the task of replacing Google Search just yet, but it can be useful in more specific contexts — including handling the drudgery that comes…

Skej’s AI meeting scheduling assistant works like adding an EA to your email

Faircado has built a browser extension that suggests pre-owned alternatives for ecommerce listings.

Faircado raises $3M to nudge people to buy pre-owned goods

Tumblr, the blogging site acquired twice, is launching its “Communities” feature in open beta, the Tumblr Labs division has announced. The feature offers a dedicated space for users to connect…

Tumblr launches its semi-private Communities in open beta

Remittances from workers in the U.S. to their families and friends in Latin America amounted to $155 billion in 2023. With such a huge opportunity, banks, money transfer companies, retailers,…

Félix Pago raises $15.5 million to help Latino workers send money home via WhatsApp

Google said today it’s adding new AI-powered features such as a writing assistant and a wallpaper creator and providing easy access to Gemini chatbot to its Chromebook Plus line of…

Google adds AI-powered features to Chromebook

The dynamic duo behind the Grammy Award–winning music group the Chainsmokers, Alex Pall and Drew Taggart, are set to bring their entrepreneurial expertise to TechCrunch Disrupt 2024. Known for their…

The Chainsmokers light up Disrupt 2024

The deal will give LumApps a big nest egg to make acquisitions and scale its business.

LumApps, the French ‘intranet super app,’ sells majority stake to Bridgepoint in a $650M deal

Featured Article

More neobanks are becoming mobile networks — and Nubank wants a piece of the action

Nubank is taking its first tentative steps into the mobile network realm, as the NYSE-traded Brazilian neobank rolls out an eSIM (embedded SIM) service for travelers. The service will give customers access to 10GB of free roaming internet in more than 40 countries without having to switch out their own existing physical SIM card or…

10 hours ago
More neobanks are becoming mobile networks — and Nubank wants a piece of the action

Infra.Market, an Indian startup that helps construction and real estate firms procure materials, has raised $50M from MARS Unicorn Fund.

MARS doubles down on India’s Infra.Market with new $50M investment

Small operations can lose customers by not offering financing, something the Berlin-based startup wants to change.

Cloover wants to speed solar adoption by helping installers finance new sales

India’s Adani Group is in discussions to venture into digital payments and e-commerce, according to a report.

Adani looks to battle Reliance, Walmart in India’s e-commerce, payments race, report says

Ledger, a French startup mostly known for its secure crypto hardware wallets, has started shipping new wallets nearly 18 months after announcing the latest Ledger Stax devices. The updated wallet…

Ledger starts shipping its high-end hardware crypto wallet

A data protection taskforce that’s spent over a year considering how the European Union’s data protection rulebook applies to OpenAI’s viral chatbot, ChatGPT, reported preliminary conclusions Friday. The top-line takeaway…

EU’s ChatGPT taskforce offers first look at detangling the AI chatbot’s privacy compliance

Here’s a shoutout to LatAm early-stage startup founders! We want YOU to apply for the Startup Battlefield 200 at TechCrunch Disrupt 2024. But you’d better hurry — time is running…

LatAm startups: Apply to Startup Battlefield 200

The countdown to early-bird savings for TechCrunch Disrupt, taking place October 28–30 in San Francisco, continues. You have just five days left to save up to $800 on the price…

5 days left to get your early-bird Disrupt passes

Venture investment into Spanish startups also held up quite well, with €2.2 billion raised across some 850 funding rounds.

Spanish startups reached €100 billion in aggregate value last year

Featured Article

Onyx Motorbikes was in trouble — and then its 37-year-old owner died

James Khatiblou, the owner and CEO of Onyx Motorbikes, was watching his e-bike startup fall apart.  Onyx was being evicted from its warehouse in El Segundo, near Los Angeles. The company’s unpaid bills were stacking up. Its chief operating officer had abruptly resigned. A shipment of around 100 CTY2 dirt bikes from Chinese supplier Suzhou…

1 day ago
Onyx Motorbikes was in trouble — and then its 37-year-old owner died

Featured Article

Iyo thinks its GenAI earbuds can succeed where Humane and Rabbit stumbled

Iyo represents a third form factor in the push to deliver standalone generative AI devices: Bluetooth earbuds.

1 day ago
Iyo thinks its GenAI earbuds can succeed where Humane and Rabbit stumbled

Arati Prabhakar, profiled as part of TechCrunch’s Women in AI series, is director of the White House Office of Science and Technology Policy.

Women in AI: Arati Prabhakar thinks it’s crucial to get AI ‘right’

AniML, the French startup behind a new 3D capture app called Doly, wants to create the PhotoRoom of product videos, sort of. If you’re selling sneakers on an online marketplace…

Doly lets you generate 3D product videos from your iPhone

Elon Musk’s AI startup, xAI, has raised $6 billion in a new funding round, it said today, as Musk shores up capital to aggressively compete with rivals including OpenAI, Microsoft,…

Elon Musk’s xAI raises $6B from Valor, a16z, and Sequoia

Indian startup Zypp Electric plans to use fresh investment from Japanese oil and energy conglomerate ENEOS to take its EV rental service into Southeast Asia early next year, TechCrunch has…

Indian EV startup Zypp Electric secures backing to fund expansion to Southeast Asia

Last month, one of the Bay Area’s better-known early-stage venture capital firms, Uncork Capital, marked its 20th anniversary with a party in a renovated church in San Francisco’s SoMa neighborhood,…

A venture capital firm looks back on changing norms, from board seats to backing rival startups