Startups

TechCrunch+ roundup: New VC rules, AI biotech investor survey, Instagram ad case study

Comment

Houses in the Sea Cliff neighborhood of San Francisco, California, US, on Thursday, Dec. 15, 2022. California home sales plunged this year as soaring interest rates held back buyers in the costly state. Photographer: David Paul Morris/Bloomberg via Getty Images
Image Credits: Bloomberg (opens in a new window) / Getty Images

When a cat is scared, it may hide under the couch; a startled fish will swim into a dark hole. And when humans feel uneasy, we tell ourselves stories.

An example: “growth at all costs” is a fairy tale made possible by cheap money that helped venture capitalists set expectations for founders — and each other — for years.

Similarly, “everyone needs 18-24 months of runway” is a nice motto, but when it takes three times longer to raise a round than it used to, it may no longer be useful advice.

“These ‘VCisms’ borne out of an era of plenty have permeated boardrooms and investor meetings everywhere,” notes Neotribes Ventures partner Rebecca Mitchem in a TechCrunch+ post this morning.


Full TechCrunch+ articles are only available to members.
Use discount code TCPLUSROUNDUP to save 20% off a one- or two-year subscription.


It’s time to ask ourselves if these VCisms are still relevant or if it’s time to change.

In a data-driven piece that looks at post-money valuations, deal sizes and dilution rates going back to 2012, Mitchem says we’re now heading into a new era where the tech industry will embrace “growth at reasonable costs.”

Founders can continue to water down their ownership by pursuing fat rounds, or they can decide to grow more slowly, which will leave everyone involved with a larger stake over time.

“While it may feel counterintuitive, given the recent market environment, the value of the equity for all parties — investors, founders and employees — is higher in the more conservative growth scenario,” says Mitchem.

Thanks very much for reading TC+ this week,

Walter Thompson
Editorial Manager, TechCrunch+
@yourprotagonist

The rules of VC are changing: Here’s what founders should be considering in the new era

6 investors discuss why AI is more than just a buzzword in biotech

Digital image of artificial intelligence human brain on black background.
Image Credits: Andriy Onufriyenko (opens in a new window) / Getty Images

Biotech firms widely use AI and machine learning to reduce R&D spending and bring products to market faster, but “the bigger question for investors is getting a better understanding of what exactly AI is attempting to model and predict,” says Shaq Vayda, principal at Lux Capital.

In her latest investor survey, Anna Heim spoke to six biotech investors about where AI creates value, short-term market shifts, and how they’d like to be approached by founders:

  • Robert Mittendorff, M.D, general partner and head of healthcare, B Capital
  • James Coates, health and human performance principal, Decisive Point
  • Shaq Vayda, principal, Lux Capital
  • Franck Lescure, partner, Elaia Partners
  • Francisco Dopazo, general partner, Humboldt Fund
  • Sarah Guo, founder, Conviction

6 investors discuss why AI is more than just a buzzword in biotech

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Row of ice creams with different amounts of scoops
Image Credits: Jonathan Knowles (opens in a new window) / Getty Images

Consumer-facing startups are spending more on platforms like TikTok and Instagram to reach customers, but which ad products offer the best return?

In a case study based on Instagram campaigns for a site that facilitates bookings for freelance beauty professionals, digital marketer Angelina Liparteliani looked at Instagram Reels, Feed Posts and Stories.

Her highly detailed breakdown includes examples of the ads used in various campaigns, the process she used for optimizing creative materials and a cost-per-click analysis that shows how she reduced CPC from $1.51 to 17 cents.

“Definitely don’t chase trends,” advises Liparteliani. “Diversify your ad strategy, test different ideas and don’t give up if your ad doesn’t show results right away.”

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Image Credits: Medcrypt (opens in a new window)

Many medical devices are just as vulnerable to cybersecurity threats as other IoT products, which is why Y Combinator graduate MedCrypt creates software to protect patients.

The company predicts that manufacturers will need to secure $1 trillion of “new and legacy” devices over the next three years, a truly tantalizing TAM.

After redacting some customer adoption details, MedCrypt’s founders shared with TC+ the 12-slide deck that helped it raise a $25 million Series B:

  • Cover slide
  • Problem slide
  • Target audience/market size slide
  • Opportunity slide
  • Mission slide
  • Product slide: Vulnerability tracking
  • Product slide: Behavior monitoring
  • Product slide: Cryptography
  • Product slide: MedISAO
  • Team slide
  • Summary/traction slide

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Dear Sophie: When can I register my employee for the H-1B lottery?

lone figure at entrance to maze hedge that has an American flag at the center
Image Credits: Bryce Durbin/TechCrunch

Dear Sophie,

We’re a pre-seed startup thinking about sponsoring an early employee’s H-1B visa to stay in the U.S. and work for us.

How does the process work?

— Seeking in San Mateo

Dear Sophie: When can I register my employee for the H-1B lottery?

A guide to navigating your first 90 days as a new CISO

Red Colored Navigational Compass on Red Background Directly Above View.
Image Credits: MirageC (opens in a new window) / Getty Images

I’m used to working under pressure, but taking a job as a chief information security officer sounds extraordinarily stressful: People are far more likely to learn about your failures than your successes.

Managing the cybersecurity needs of an entire organization is “a big job that touches just about every part of the organization,” says Heather Gantt-Evans, CISO at SailPoint.

She’s written a guide for incoming CISOs that contains a framework for setting goals, creating action plans and, most importantly, documenting risk.

“The first 90 days of a new CISO’s term are critical,” writes Gantt-Evans. “They’re the best chance you’ll ever have to research, gather documentation and assess where things stand and how they can be improved.”

A guide to navigating your first 90 days as a new CISO

In a turbulent market, it’s time to get methodical about sales

Teacher preparing pencils for school day; aligning product team with product vision
Image Credits: Peter Dazeley (opens in a new window) / Getty Images

Many SaaS sales teams haven’t worked in an environment where so many customers are cutting back on spending, and it shows: When everyone’s in the mood to buy, it’s less important to develop a critical understanding of your customer’s needs.

“Sellers shouldn’t hop right into pushing features,” advises Steve Goldberg, chief revenue officer at Salesloft. “They should illustrate the unsustainable nature of a customer’s current behaviors and processes.”

In this post, Goldberg looks at MEDDPICC and design thinking, two sales methodologies that are “particularly effective when times get tough.”

In a turbulent market, it’s time to get methodical about sales

More TechCrunch

Waymo has voluntarily issued a software recall to all 672 of its Jaguar I-Pace robotaxis after one of them collided with a telephone pole. This is Waymo’s second recall. The…

Waymo issues second recall after robotaxi hit telephone pole

The hotel guest management technology company’s platform digitizes the hotel guest journey from post-booking through checkout.

Insight Partners backs Canary Technologies’ mission to elevate hotel guest experiences

The TechCrunch team runs down all of the biggest news from the Apple WWDC 2024 keynote in an easy-to-skim digest.

Here’s everything Apple announced at the WWDC 2024 keynote, including Apple Intelligence, Siri makeover

InScope leverages machine learning and large language models to provide financial reporting and auditing processes for mid-market and enterprises.

VC Sheel Mohnot leads $4.3M seed in automated financial reporting fintech InScope

Venture fundraising has been a slog over the last few years, even for firms with a strong track record. That’s Foresite Capital’s experience. Despite having 47 IPOs, 28 M&As and…

Foresite Capital raises $900M sixth fund for investing in healthcare and life sciences companies

A year ago, Databricks acquired MosaicML for $1.3 billion. Now rebranded as Mosaic AI, the platform has become integral to Databricks’ AI solutions. Today, at the company’s Data + AI…

Databricks expands Mosaic AI to help enterprises build with LLMs

RetailReady targets the $40 billion compliance market to help reduce the number of retail compliance losses that shippers incur annually due to incorrectly shipped packages.

YC grad, RetailReady raises $3.3M for an AI warehouse app that hopes to save brands billions

Since its launch in 2013, Databricks has relied on its ecosystem of partners, such as Fivetran, Rudderstack, and dbt, to provide tools for data preparation and loading. But now, at…

Databricks launches LakeFlow to help its customers build their data pipelines

A big shoutout to the early-stage founders who missed the application window for the Startup Battlefield 200 (SB 200) at TechCrunch Disrupt. We have exciting news just for you! You…

Bonus: An extra week to apply to Startup Battlefield 200

When one of the co-creators of the popular open-source stream-processing framework Apache Flink launches a new startup, it’s worth paying attention. Stephan Ewen was among the founding team of the…

Restate raises $7M for its lightweight workflows-as-code platform

With most residential solar panels installed by smaller companies, customer experience can be a mixed bag. To try to address the quality and consistency problem, Civic Renewables is buying small…

Civic Renewables is rolling up residential solar installers to improve quality and grow the market

Small VC firms require deep trust, mutual support, and long-term commitment among the partners —a kinship that, in many ways, resembles a family dynamic. Colin Anderson (Palantir’s ex-CFO and former…

Friends & Family Capital, a fund founded by ex-Palantir CFO and son of IVP’s founder, unveils third $118M fund

Fisker is issuing the first recall for its all-electric Ocean SUV because of problems with the warning lights, according to new information published by the National Highway Traffic Safety Administration.…

Fisker’s troubled Ocean SUV gets its first recall

Gorilla, a Belgian company that serves the energy sector with real-time data and analytics for pricing and forecasting, has raised €23 million ($25 million) in a Series B round led…

Gorilla, a Belgian startup that helps energy providers crunch big data, raises $25M

South Korea’s fabless AI chip industry saw a slew of fundraising events over the last couple of years as demand for hardware to power AI applications skyrocketed, and it seems…

Fabless AI chip makers Rebellions and Sapeon to merge as competition heats up in global AI hardware industry

Here’s a list of third-party apps that were Sherlocked by Apple at this year’s WWDC.

The apps that Apple Sherlocked at WWDC 2024

Black Semiconductor, which is developing a chip-connecting technology based on graphene, has raised $273M in a combination of private and public funding. 

Black Semiconductor nabs $273M in Germany to supercharge how chips work together

Featured Article

Let there be Light! Danish startup exits stealth with $13M seed funding to bring AI to general ledgers

It’s not the sexiest of subject matters, but someone needs to talk about it: The CFO tech stack — software used by the chief financial officers of the world — is ripe for disruption. That’s according to Jonathan Sanders, CEO and co-founder of fledgling Danish startup Light, which exits stealth…

8 hours ago
Let there be Light! Danish startup exits stealth with $13M seed funding to bring AI to general ledgers

Fresh off the success of its first mission, satellite manufacturer Apex has closed $95 million in new capital to scale its operations.  The Los Angeles-based startup successfully launched and commissioned…

Apex’s off-the-shelf satellite bus business attracts $95M in new funding

After educating the D.C. market, YC aims to leverage its influence, particularly in areas like competition policy.

DC’s political class doesn’t know Y Combinator exists — yet

Lina Khan says the FTC wants to be effective in its enforcement strategy, which is why it has been taking on lawsuits that “go up against some of the big…

FTC Chair Lina Khan tells TechCrunch the agency is pursuing the ‘mob bosses’ in Big Tech

With dozens of antitrust cases and close to a hundred on the consumer protection side, the agency is now turning to innovative tactics to help it fight fraud, particularly in…

FTC Chair Lina Khan shares how the agency is looking at AI

The ability to pause your activity rings is a minor feature update for most, but for those of us who obsess about such things to an unhealthy degree, it’s the…

Apple Watch is finally adding a feature I’ve been requesting for years

Featured Article

Why Apple is taking a small-model approach to generative AI

It’s a very Apple approach in the sense that it prioritizes a frictionless user experience above all.

16 hours ago
Why Apple is taking a small-model approach to generative AI

When generative AI tools started making waves in late 2022 after the launch of ChatGPT, the finance industry was one of the first to recognize these tools’ potential for speeding…

Linq raises $6.6M to use AI to make research easier for financial analysts

In addition to the federal funding, the state of New Mexico — where SolAero is based — committed to providing financing and incentives that value $25.5 million.

Biden administration looks to give Rocket Lab $24M to boost space-grade solar cell production

Some of the new Apple Intelligence features that Apple debuted at WWDC 2024 don’t even feel like AI, they just feel like smarter tools. 

Apple’s AI, Apple Intelligence, is boring and practical — that’s why it works

Jordan Meyer and Mathew Dryhurst founded Spawning AI to create tools that help artists exert more control over how their works are used online. Their latest project, called Source.Plus, is…

Spawning wants to build more ethical AI training datasets

After leading the social media landscape, TikTok appears to be interested in challenging Google’s dominance in search. The company confirmed to TechCrunch that it’s testing the ability for users to…

TikTok comes for Google as it quietly rolls out image search capabilities in TikTok Shop

General Motors is investing $850 million into Cruise as the autonomous vehicle subsidiary slowly makes its way back to testing in Phoenix, Dallas and, as of Tuesday, Houston. GM’s CFO…

GM gives Cruise $850M lifeline as it relaunches robotaxis in Houston