Venture

Cultured meat startup Prolific Machines unveils its ‘Henry Ford approach’ to cell growth

Comment

Prolific Machines cultured meat
Image Credits: Prolific Machines

The global cultured meat market is poised to reach half a billion dollars by 2030; however, this kind of technology is still very much in the R&D phase for a lot of companies that have emerged over the past five years.

Cultured meat, also known as cultivated meat, is animal meat, but instead of slaughtering the animal to get it, cells are collected from the animal and cultivated in a lab where they are then assembled into a structure of tissue that resembles the same meat we all eat.

We’ve seen a few cultured meat companies unveil their products. For example, Novel Farms has a pork loin, while Bluu Seafood, a German company developing lab-grown seafood, debuted its fish sticks and fish balls last month. Same for Dutch-based Meatable with its sausages, SCiFi Foods with its burgers, and chicken for UPSIDE Foods.

However, the manufacturing process for cultured meat has historically been “both very difficult and very expensive,” Prolific Machines’ co-founder and CEO Deniz Kent told TechCrunch. That’s what his company is out to change.

“You have to use these growth media proteins which are some of the most expensive things — one of the proteins we are replacing is like 30,000 times more expensive than a gram of gold,” he added. “It’s really hard to scale anything for this reason because you have to use these proteins.”

Novel Farms flexes its pork loin ‘muscle’ following future equity investment

Kent, who has expertise in stem cell biology, explained that these proteins have been used for decades, mainly in the biopharmaceutical industry. The technology works on pharmaceutical products that have big budgets, but not so good when you are trying to make a high-volume, low-margin product like meat, he added.

While having the idea for better proteins, he met physicist Max Huisman and machine learning engineer Declan Jones and convinced them to quit their jobs and form Prolific Machines with him in 2020.

That said, Prolific Machines believes it has a unique manufacturing approach for cultured meat cells and is coming out of stealth mode with $42 million in combined seed and Series A funding to build what Kent calls an “assembly line for biology.”

The company aims to do for biology what Henry Ford did for automobiles at the turn of the 20th century. Its technology, still in its early stages, is a way to grow and control cells without the need for any of those expensive recombinant proteins for cell production, he said. Prolific Machines will bring products to market, but will also license its infrastructure to other cultured meat companies.

“Back then, nobody really owned cars apart from super-rich people. What really changed things was Ford,” Kent said. “They built the assembly line for cars and found a way to manufacture cars at a price that normal people could afford. That transformed the industry because then you went from hundreds of car companies to only three companies having over 70% of the market.”

He believes the same thing is going to happen in the cultured meat industry: There are hundreds of companies right now, but “most of them will die because they won’t have a way to manufacture cultured meat cheap enough. The ones that can find a way will survive,” he added.

Prolific Machines was part of SOSV’s IndieBio program in 2021. SOSV led Prolific Machines’ pre-seed round. Meanwhile, for its new capital infusion, the seed-round portion was led by Arvind Gupta, partner at Mayfield, and the Series A by Bill Gates–founded Breakthrough Energy Ventures.

“I never intended to invest in another cultured meat company, but when Deniz showed me what they were doing, I was blown away by the creativity in their approach to reinvent the assembly line for food production,” Gupta said in a written statement. “It is my goal to help reverse climate change by partnering with incredible teams, and I am convinced Prolific Machines will be a winner in the race for sustainable food production.”

Joining in on the two rounds was a group of VC firms and individual investors, including David Adelman, Mark Cuban, The Kraft Family, David Rubenstein, Michael Rubin, Breyer Capital, The SALT Fund, Purple Orange Ventures, Fred Blackford, Jake Poliskin, Matt Katz and Baruch Future Ventures. Add to that a group of celebrities and restaurateurs, including Kevin Love, Tobias Harris, Meek Mill, Ciara and Russell Wilson, Emily Ratajkowski, Maverick Carter, Sean Feeney, Michael Schulson, Mark Bucher and RJ Melman.

Kent said the Series A was raised a year ago, but the company is coming out of stealth now as it prepares to raise a quite hefty “$170 million-ish” Series B in the first quarter of 2023. The new funding will go toward building a 25,000-square-foot headquarters in Emeryville, California, and ramp up hiring to expand its assembly line programs, including fish, poultry and beef.

Meanwhile, he expects the facility to be done in spring 2023. Plans for the company’s first product include an unstructured Wagyu, which means ground meat. Prolific Machines also has a number of high-profile chefs — none that Kent could name now — who have agreed to partner with the company and use its first cultured meat products.

Is cell-cultured meat ready for prime time?

More TechCrunch

Tech enthusiasts and entrepreneurs, the clock is ticking! With just 72 hours remaining until the early-bird ticket deadline for TechCrunch Disrupt 2024, now is the time to secure your spot…

72 hours left of the Disrupt early-bird sale

Avendus, the top investment bank for venture deals in India, confirmed on Wednesday it is looking to raise up to $350 million for its new private equity fund.  The new…

Avendus, India’s top venture advisor, confirms it’s looking to raise a $350 million fund

China has closed a third state-backed investment fund to bolster its semiconductor industry and reduce reliance on other nations, both for using and for manufacturing wafers — prioritizing what is…

China’s $47B semiconductor fund puts chip sovereignty front and center

Apple’s annual list of what it considers the best and most innovative software available on its platform is turning its attention to the little guy.

Apple’s Design Awards nominees highlight indies and startups, largely ignore AI (except for Arc)

The spyware maker’s founder, Bryan Fleming, said pcTattletale is “out of business and completely done,” following a data breach.

Spyware maker pcTattletale says it’s ‘out of business’ and shuts down after data breach

AI models are always surprising us, not just in what they can do, but what they can’t, and why. An interesting new behavior is both superficial and revealing about these…

AI models have favorite numbers, because they think they’re people

On Friday, Pal Kovacs was listening to the long-awaited new album from rock and metal giants Bring Me The Horizon when he noticed a strange sound at the end of…

Rock band’s hidden hacking-themed website gets hacked

Jan Leike, a leading AI researcher who earlier this month resigned from OpenAI before publicly criticizing the company’s approach to AI safety, has joined OpenAI rival Anthropic to lead a…

Anthropic hires former OpenAI safety lead to head up new team

Welcome to TechCrunch Fintech! This week, we’re looking at the long-term implications of Synapse’s bankruptcy on the fintech sector, Majority’s impressive ARR milestone, and more!  To get a roundup of…

The demise of BaaS fintech Synapse could derail the funding prospects for other startups in the space

YouTube’s free Playables don’t directly challenge the app store model or break Apple’s rules. However, they do compete with the App Store’s free games.

YouTube’s free games catalog ‘Playables’ rolls out to all users

Featured Article

A comprehensive list of 2024 tech layoffs

The tech layoff wave is still going strong in 2024. Following significant workforce reductions in 2022 and 2023, this year has already seen 60,000 job cuts across 254 companies, according to independent layoffs tracker Layoffs.fyi. Companies like Tesla, Amazon, Google, TikTok, Snap and Microsoft have conducted sizable layoffs in the first months of 2024. Smaller-sized…

16 hours ago
A comprehensive list of 2024 tech layoffs

OpenAI has formed a new committee to oversee “critical” safety and security decisions related to the company’s projects and operations. But, in a move that’s sure to raise the ire…

OpenAI’s new safety committee is made up of all insiders

Time is running out for tech enthusiasts and entrepreneurs to secure their early-bird tickets for TechCrunch Disrupt 2024! With only four days left until the May 31 deadline, now is…

Early bird gets the savings — 4 days left for Disrupt sale

AI may not be up to the task of replacing Google Search just yet, but it can be useful in more specific contexts — including handling the drudgery that comes…

Skej’s AI meeting scheduling assistant works like adding an EA to your email

Faircado has built a browser extension that suggests pre-owned alternatives for ecommerce listings.

Faircado raises $3M to nudge people to buy pre-owned goods

Tumblr, the blogging site acquired twice, is launching its “Communities” feature in open beta, the Tumblr Labs division has announced. The feature offers a dedicated space for users to connect…

Tumblr launches its semi-private Communities in open beta

Remittances from workers in the U.S. to their families and friends in Latin America amounted to $155 billion in 2023. With such a huge opportunity, banks, money transfer companies, retailers,…

Félix Pago raises $15.5 million to help Latino workers send money home via WhatsApp

Google said today it’s adding new AI-powered features such as a writing assistant and a wallpaper creator and providing easy access to Gemini chatbot to its Chromebook Plus line of…

Google adds AI-powered features to Chromebook

The dynamic duo behind the Grammy Award–winning music group the Chainsmokers, Alex Pall and Drew Taggart, are set to bring their entrepreneurial expertise to TechCrunch Disrupt 2024. Known for their…

The Chainsmokers light up Disrupt 2024

The deal will give LumApps a big nest egg to make acquisitions and scale its business.

LumApps, the French ‘intranet super app,’ sells majority stake to Bridgepoint in a $650M deal

Featured Article

More neobanks are becoming mobile networks — and Nubank wants a piece of the action

Nubank is taking its first tentative steps into the mobile network realm, as the NYSE-traded Brazilian neobank rolls out an eSIM (embedded SIM) service for travelers. The service will give customers access to 10GB of free roaming internet in more than 40 countries without having to switch out their own existing physical SIM card or…

23 hours ago
More neobanks are becoming mobile networks — and Nubank wants a piece of the action

Infra.Market, an Indian startup that helps construction and real estate firms procure materials, has raised $50M from MARS Unicorn Fund.

MARS doubles down on India’s Infra.Market with new $50M investment

Small operations can lose customers by not offering financing, something the Berlin-based startup wants to change.

Cloover wants to speed solar adoption by helping installers finance new sales

India’s Adani Group is in discussions to venture into digital payments and e-commerce, according to a report.

Adani looks to battle Reliance, Walmart in India’s e-commerce, payments race, report says

Ledger, a French startup mostly known for its secure crypto hardware wallets, has started shipping new wallets nearly 18 months after announcing the latest Ledger Stax devices. The updated wallet…

Ledger starts shipping its high-end hardware crypto wallet

A data protection taskforce that’s spent over a year considering how the European Union’s data protection rulebook applies to OpenAI’s viral chatbot, ChatGPT, reported preliminary conclusions Friday. The top-line takeaway…

EU’s ChatGPT taskforce offers first look at detangling the AI chatbot’s privacy compliance

Here’s a shoutout to LatAm early-stage startup founders! We want YOU to apply for the Startup Battlefield 200 at TechCrunch Disrupt 2024. But you’d better hurry — time is running…

LatAm startups: Apply to Startup Battlefield 200

The countdown to early-bird savings for TechCrunch Disrupt, taking place October 28–30 in San Francisco, continues. You have just five days left to save up to $800 on the price…

5 days left to get your early-bird Disrupt passes

Venture investment into Spanish startups also held up quite well, with €2.2 billion raised across some 850 funding rounds.

Spanish startups reached €100 billion in aggregate value last year

Featured Article

Onyx Motorbikes was in trouble — and then its 37-year-old owner died

James Khatiblou, the owner and CEO of Onyx Motorbikes, was watching his e-bike startup fall apart.  Onyx was being evicted from its warehouse in El Segundo, near Los Angeles. The company’s unpaid bills were stacking up. Its chief operating officer had abruptly resigned. A shipment of around 100 CTY2 dirt bikes from Chinese supplier Suzhou…

2 days ago
Onyx Motorbikes was in trouble — and then its 37-year-old owner died